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Ashtech Science

Prosil™ C18 HPLC Columns

Reliable, high‑performance C18 columns for routine and advanced HPLC applications
Prosil HPLC Columns
Prosil™ C18 HPLC Columns
SKU: PROSIL-C18-HPLC-COLUMNS

Reliable, high‑performance C18 columns for routine and advanced HPLC applications

Contact us for more information and pricing on our extensive range of Prosil HPLC Columns

Ashtech Science: Prosil™ C18 HPLC Columns

Reliable, high‑performance C18 columns for routine and advanced HPLC applications

Ashtech Science’s Prosil™ C18 HPLC columns are engineered to deliver excellent peak shape, reproducibility, and long column lifetime—making them a cost‑effective upgrade for many established C18 methods. Manufactured in partnership with a leading UK producer, these columns combine modern Type B silica technology with proven surface chemistry to ensure consistent, dependable performance across a wide range of analytical workflows.


Key Benefits

  • Improved peak shape through advanced Type B silica
  • Long column lifetime and enhanced robustness
  • Excellent reproducibility batch‑to‑batch
  • Seamless method compatibility with many legacy C18 columns
  • Economical alternative without sacrificing performance

Product Overview

Prosil™ C18 columns are designed for both routine QC and demanding analytical separations. The optimised stationary phase chemistry provides a balanced combination of efficiency, durability, and retention characteristics. These columns allow laboratories to update existing methods while minimising re‑validation requirements—ideal for cost‑conscious environments.


Technical Specifications

  • Stationary phase: C18 (ODS)
  • Silica type: Type B silica
  • Surface area: 175 m²/g
  • Pore size: 140 Å
  • Carbon load: 11% C
  • Formats available: Analytical columns and guard columns
  • Manufacturing: UK manufactured

Suitable Alternatives To

  • Alltech ODS2
  • Alltech Exsil C18
  • Hypersil
  • Hypersil BDS
  • Nucleosil 120 C18
  • Pinnacle C18
  • Spherisorb ODS1 / ODS2
  • Supelcosil LC18
  • Ultrasphere C18
  • YMC ODS‑A
  • Zorbax Rx‑C18

Third‑party brand names are listed for comparison purposes only.


Why Choose Prosil™ C18?

  • Upgrade existing HPLC methods with minimal disruption
  • Achieve consistent performance in routine analyses
  • Reduce operating costs compared with many legacy brands
  • Benefit from Ashtech Science’s technical expertise

Ordering Information

Prosil™ C18 columns are available in a wide range of dimensions and particle sizes to support routine and advanced HPLC applications. Guard columns are also available.

Ashtech Science: Prosil™ C18 HPLC Columns

Column Type Length (mm) Internal Diameter (mm) Particle Size (µm) Notes
Analytical column 50 2.1 / 3.0 / 4.6 3, 5 High‑throughput and fast separations
Analytical column 100 2.1 / 3.0 / 4.6 3, 5 Routine analytical use
Analytical column 150 2.1 / 3.0 / 4.6 3, 5 High‑efficiency separations
Analytical column 250 4.6 5 Extended resolution
Guard column Matching IDs Matching Protects analytical column

Additional dimensions and configurations may be available on request.

Ordering & Enquiries

To request a quotation or technical support, please specify column length, internal diameter, and particle size when contacting our sales team.
sales@ashtechscience.com — www.ashtechscience.com


Product Range

Part Number Description
ASH-HPLC-C18321100 Prosil C18 3µm HPLC Column 2.1mm dia., 100mm length
ASH-HPLC-C18330100 Prosil C18 3µm HPLC Column 3mm dia., 100mm length
ASH-HPLC-C18346100 Prosil C18 3µm HPLC Column 4.6mm dia., 100mm length
ASH-HPLC-C18321150 Prosil C18 3µm HPLC Column 2.1mm dia., 150mm length
ASH-HPLC-C18330150 Prosil C18 3µm HPLC Column 3mm dia., 150mm length
ASH-HPLC-C18346150 Prosil C18 3µm HPLC Column 4.6mm dia., 150mm length
ASH-HPLC-C18321250 Prosil C18 3µm HPLC Column 2.1mm dia., 250mm length
ASH-HPLC-C18330250 Prosil C18 3µm HPLC Column 3mm dia., 250mm length
ASH-HPLC-C18346250 Prosil C18 3µm HPLC Column 4.6mm dia., 250mm length
ASH-HPLC-C18521100 Prosil C18 5µm HPLC Column 2.1mm dia., 100mm length
ASH-HPLC-C18530100 Prosil C18 5µm HPLC Column 3mm dia., 100mm length
ASH-HPLC-C18546100 Prosil C18 5µm HPLC Column 4.6mm dia., 100mm length
ASH-HPLC-C18521150 Prosil C18 5µm HPLC Column 2.1mm dia., 150mm length
ASH-HPLC-C18530150 Prosil C18 5µm HPLC Column 3mm dia., 150mm length
ASH-HPLC-C18546150 Prosil C18 5µm HPLC Column 4.6mm dia., 150mm length
ASH-HPLC-C18521250 Prosil C18 5µm HPLC Column 2.1mm dia., 250mm length
ASH-HPLC-C18530250 Prosil C18 5µm HPLC Column 3mm dia., 250mm length
ASH-HPLC-C18546250 Prosil C18 5µm HPLC Column 4.6mm dia., 250mm length
ASH-HPLC-GCC1832 Prosil C18 3µm Guard Column Kit 2mm dia (pk4)
ASH-HPLC-GCC1834 Prosil C18 3µm Guard Column Kit 4mm dia (pk4)
ASH-HPLC-GCC1852 Prosil C18 5µm Guard Column Kit 2mm dia (pk4)
ASH-HPLC-GCC1854 Prosil C18 5µm Guard Column Kit 4mm dia (pk4)
ASH-HPLC-GCH Guard Column Holder
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